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Injectafer is approved to treat iron deficiency anemia (IDA). Remember that it is best to get your vitamins and minerals from food whenever possible. However, consuming large amounts of alcohol can actually cause anemia in some people. Injectafer isnt available in a generic form. Call your doctor for instructions if you miss an appointment for your Venofer injection. Can diet help improve depression symptoms? Keep all drugs in a safe place. Injectafer and Venofer have different approved uses, but theyre both used to treat IDA in people with CKD. Total cumulative Venofer dose = number of 100mg ampoules for Hb increase. Selected from data included with permission and copyrighted by First Databank, Inc. How long it takes for the bodyto break down the meds matters and some peoples bodies simply take longer than others. Pain, swelling, or redness at the injection site may occur. To make sure Venofer injection is safe for you, tell your doctor if you have: hemochromatosis or iron overload (the buildup of excess iron). Symptoms of a severe allergic reaction can include: Because of the risk of allergic reaction with Injectafer, your healthcare professional will monitor you for at least 30 minutes after you get each dose of the drug. weakness. However, some people may have weight changes as they have improvement in their anemia, which Injectafer is used to treat. Your body may also need more iron if you use the drug erythropoietin to help make new red blood cells.Iron is an important part of your red blood cells and is needed to transport oxygen in the body. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Venofer only for the indication prescribed. Call your doctor right away if you have chest pain, cough or the need to cough, dizziness, passing out, shortness of breath, sweating, or throat tightness. Not all possible drug interactions are listed here. The infusion will take between 15-30 minutes if it is given in. If that happens, and your doctor thinks Injectafer is a good treatment option for you, you can receive another treatment course of the drug. Drug class: Iron products. chest pain. People with IDA have low blood levels of hemoglobin. Examples of other drugs that may be used to treat IDA include: Your doctor will recommend the drug thats right for you depending on the severity of your anemia and any other medical conditions you may have. People who weigh 110 pounds (about 50 kilograms) or more will receive two separate Injectafer doses of 750 milligrams each. The actual price youll pay for either drug depends on your insurance plan, your location, and the pharmacy you use. If you would like to report to the FDA a side effect youve had with Injectafer, you can do so through MedWatch. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. If you notice any changes to your normal blood pressure, call your doctor right away. Keep in mind that the risk of certain pregnancy-related problems can be increased if iron deficiency anemia (IDA) is left untreated. If you have questions about side effects, call your doctor. The way thatprescription drugsand evenover-the-countermedications interact with a body is influenced by manyfactors. For people with certain medical implants, such as pacemakers, an MRI may pose an . For instance, there are some experts who believe there are long-lastingside effectsfromCOVIDthat were not aware of just yet. Effectiveness of Injectafer compared with iron thats taken by mouth. signs of inflammation in the lining of your stomach --pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, fever. % Click below for effective ways to alleviate the discomfort felt fromside effects and learn how to get a free Medication and Drug Reaction DNAReport. Its not known for sure how often this condition occurred during clinical trials, or if it occurred at all during the trials. Always review your medical history with the treatingphysician. With slow IV injection, the drug is given as a single, slow injection into your vein. How is Venofer (iron sucrose) given? fluid retention, especially in your arms, legs, or feet, people who took Feraheme had their hemoglobin level increase, on average, by 1.38 grams per deciliter (g/dL), people who took ferric carboxymaltose had their hemoglobin level increase, on average, by 1.63 g/dL, having strange cravings to eat items that arent food, such as ice, people who took Injectafer had their hemoglobin level increase, on average, by 1.6 grams per deciliter (g/dL), people who kept taking iron by mouth had their hemoglobin level increase, on average, by 0.8 g/dL, people who took Injectafer had their hemoglobin level increase, on average, by 2.9 g/dL, people who took the other intravenous iron product had their hemoglobin level increase, on average, by 2.2 g/dL, people who took Injectafer had their hemoglobin level increase by an average of 1.1 g/dL, people who took Venofer had their hemoglobin level increase by an average of 0.9 g/dL, cannot tolerate or have shown a poor response to oral iron, or, have been diagnosed with chronic kidney disease (CKD) that is non-dialysis dependent. This includes your doctors, nurses, pharmacists, and dentists. But for other people, their IDA returns after treatment with Injectafer. This product may contain inactive ingredients, which can cause allergic reactions or other problems. The actual price youll pay depends on your insurance plan and any copays, your location, and the pharmacy you use. But call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. Iron sucrose injection has a molecular weight of approximately 34,000 - 60,000 daltons and a proposed structural formula: Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. Copyright 1996-2023 Cerner Multum, Inc. Learn more about these, as well as the symptoms, diagnosis, and treatments. But its only approved for use in people with CKD who may or may not need dialysis. All rights reserved. monitor along with your hemoglobin and red blood cell count: The Venofer patient brochure provides information and support for CKD patients (2 years and older) with IDA. . For more information about taking Injectafer during pregnancy, see the section Injectafer and pregnancy above. You may report side effects to the FDA at 1-800-332-1088. In one study, people were given either Injectafer or an iron replacement drug called Venofer. treatment schedule in further detail. This is a sudden response affecting the entire body, which sometimes happens to people who are allergic to peanuts or beestings. Back pain. Hes an expert in genetic testing, genetic analysis, andprecision medicine. Feraheme also comes as a liquid thats given by IV infusion. Examples of thisinclude: Not allside effectslast forever. Injectafer is approved for use in adults who either: Injectafer contains the active drug ingredient ferric carboxymaltose. This could happen because Injectafer helps increase their hemoglobin levels, but it doesnt address the underlying cause of their anemia. Side effects like nausea and low blood pressure are common with most iron infusions. If you miss an appointment for your Injectafer dose, youll need to call your doctors office. 1xo`[kg'#KS#.#`uv:PM1+Ob`>y/8:6Ghl:y9B+-,9m[ These changes could help improve your anemia on a long-term basis. Joint pain. Canada residents can call a provincial poison control center. . Your doctor will do laboratory tests to monitor your response. For some people, it may be OK to continue taking a multivitamin that contains iron. You must check to make sure that it is safe for you to take Venofer with all of your drugs and health problems. If you come into contact with Red Tide, it can cause respiratory irritation, coughing, and sneezing. Innovators Monograph In the second group, some people switched from taking iron by mouth to taking Injectafer. . Common side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting; diarrhea; If you do breastfeed while youre taking Injectafer, the drugs manufacturer recommends that you monitor your child for side effects of the drug. Maintain a well-balanced diet, and follow any dietary guidelines as directed by your doctor. For example, if someone takes 100 mg of a drug, only half of it will be in the bloodstream in a couple ofhours. But for other people, their anemia may come back after Injectafer treatment. Iron is also necessary for your bone marrow to build healthy new red blood cells and provide oxygen to your . Your doctor will monitor your hemoglobin level to tell if Injectafer is working for you. Venofer may reduce the absorption of iron preparations taken by mouth. While this may seem like it would be out of a persons body quickly, the rate of it being broken down is much slower afterward. Dr. Brandon ColbyMDis a US physician specializingin the personalized prevention of disease through the use of genomic technologies. 2. The information provided is not intended to replace your healthcare provider's medical advice. Injectafer and Feraheme have different approved uses, but theyre both used to treat IDA in certain adults. The iron released by this drug does pass into human breast milk. Venofer (iron sucrose) can also be mixed in a saline solution and given through an IV over a longer time. Venofer (iron sucrose) is given as an injection into the veins (intravenously or IV) by a trained healthcare provider. Call your doctor for medical advice about side effects. But its important to note that these studies werent designed to show whether Injectafer is safe to use during pregnancy. ByDr. A shortage of iron can cause health problems. In this group, after 35 days of treatment: Effectiveness of Injectafer compared with a different IV iron product. Review our medical disclaimer. Its important to note that youll get Injectafer doses from a doctor or healthcare professional in a medical facility. In one study, treatment with Injectafer was compared with that of iron thats taken by mouth. In severe cases, it can cause asthma-like symptoms, such as wheezing and difficulty breathing. Its given by either intravenous (IV) infusion or slow IV injection. Learn how to store and discard medical supplies safely. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. Injectafer is available only as a brand-name medication. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Note: The Food and Drug Administration (FDA) tracks side effects of drugs they have approved. What are the side effects of Venofer? Do not start, stop, or change the dose of any drug without checking with your doctor. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. In clinical studies, people who took Injectafer still had iron in their system that was released by the drug 24 days after theyd gotten their injection. Change in taste. Sharing this information can help you avoid potential interactions. Does Venofer Vial interact with other drugs you are taking? *Patients are calculated based on an estimated annual cumulative dose. endobj If administering via IV infusion, up to 750 mg of Injectafer should be diluted in no more than 250 mL of sterile 0.9% sodium chloride solution (NaCl). This survey is being conducted by the WebMD marketing sciences department. Procedure Details For this purpose, Injectafer is approved for use in adults who either: Venofer is also approved to treat IDA. Injectafer is approved to treat iron deficiency anemia (IDA) in certain adults with the condition. Weight influences how fast medication breaks down in the body, so it also affects how longside effectswill last. Common MRI side effects include dizziness, anxiety, headache, nausea, hearing loud noises, and feeling chilled or hot in the MRI scanner. Side effectswill last a very long time if the cause of them is not resolved. Which tests can diagnose iron deficiency anemia? stream Theseside effectsmay last as long as they are undercancer treatment. However, side effects at the 150 mg dose may indicate that you might not . Symptoms of overdosage include drowsiness, mental confusion, dizziness, diarrhea and vomiting etc. If you have questions about drug interactions that may affect you, ask your doctor or pharmacist. People who are ongoingcancer treatmentwithradiation therapyor takingchemotherapy drugsmay be more susceptible toside effects. With CKD, your kidneys dont function properly, which can lead to your body having problems using iron. Allergic reaction As with most drugs, some people can have an allergic reaction after taking Injectafer. What should I know regarding pregnancy, nursing and administering Venofer Vial to children or the elderly. Venofer may cause significant hypotension (decreased blood pressure). After getting one treatment course of Injectafer, you typically wont need another dose of the drug again unless your anemia comes back. Youll receive doses of either drug by a healthcare professional at a medical facility. Brandon ColbyMD, a medical expert specializing in preventive medicine and clinicalgenomics. (A generic drug is an exact copy of the active drug in a brand-name medication.) There are currently no generic forms of either drug. The infusion concentration should not be less than 2 mg of Injectafer per mL of solution. Read all information given to you. The body cannot metabolize such a high dose fast enough, so it ends up affecting a part of the body it wasnt intended to, such as the stomach.

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